Major Laboratories Department
The Major Laboratories Department includes 8 research units:
- Cancer Research and Advanced Therapy Unit
- Applied Chemistry Unit
- Pharmacokinetics and Pharmaceutics Research Unit
- Microbiology and Immunology Research Unit
- Environmental Sciences and Biomaterials Research Unit
- Biochemistry Research Unit
- Organic and Physical Chemistry Research Unit
- Analytical and Inorganic Chemistry Unit
These units provide advanced equipment and comprehensive research support to enhance research collaboration and scientific development across various fields.
1. Cancer Research and Advanced Therapy Unit
This unit aims to advance the understanding of the causes and mechanisms of cancer and to develop new techniques and therapies to fight the disease. It is focused on improving the effectiveness of current treatments and innovating new methods for early diagnosis and prevention. The unit operates through interdisciplinary collaboration, bringing together experts from clinical medicine, medical genetics, and oncology research.
Services Offered:
· Cytotoxicity Testing
· Apoptosis (Programmed Cell Death) Analysis
· Cellular Enzyme Profiling
· Organic Compound Synthesis
· Computational Modeling and Simulation
· Toxicology Testing
· Protein and Metabolite Profiling
Available Equipment:
- Organic Synthesizer
- High-Performance Liquid Chromatography (HPLC)
- Liquid Chromatography-Mass Spectrometry (LCMS)
- Gas Chromatography-Mass Spectrometry (GCMS-MS)
- Thermogravimetric Analysis/ Differential Scanning Calorimetry (TGA/DSC)
- Nano Spray Dryer
- Western Blot System
- UV Spectrophotometer
- ELISA Reader
- Flow Cytometer
- Light and Fluorescent Microscope
- Cell Culture Unit
2. Pharmacokinetics and Pharmaceutics Laboratory
The unit is focused on developing new techniques to analyze drug kinetics and determine drug parameters, which helps improve the effectiveness of treatments and reduce side effects. This field also involves studying advanced drug interactions and technological updates in directing drugs more precisely to their intended targets.
Services Offered:
- Disintegration Testing
- Dissolution Testing
- Pharmacokinetic Analysis
Available Equipment:
- Disintegration Tester
- Dissolution Tester
- FTIR (Fourier Transform Infrared Spectrometer)
- Precision Balances
- Cell Culture Unit
3. Microbiology and Immunology Unit
The Microbiology and Immunology Unit is equipped with specialized infrastructure and advanced equipment to support research in this field. This unit serves as a hub for scientific experiments and laboratory analyses aimed at understanding the structure and function of microorganisms, including bacteria, viruses, and fungi.
Services Offered:
Antimicrobial Effectiveness Testing (AET)
Microbial Identification Testing
Minimum Inhibitory Concentration (MIC) Testing
Minimum Bactericidal Concentration (MBC) Testing
Training and Consultation Services
Available Equipment:
- Bacteria identification device
- Specialized incubators
- Sterilization devices
- Optical microscope
- PCR machine
- ELISA reader
Physiology and Biochemistry Research Unit
This unit contributes to expanding knowledge about the body's processes at the chemical and molecular levels, thereby aiding in the development of treatment and diagnostic methods and improving healthcare.
Available Equipment:
- Amino Acid Analyzer
- Western Blot Device
5. Hematology Research Unit
The laboratory is equipped with a variety of analytical equipment for studying and diagnosing blood-related diseases. It also features tools for cellular analysis and molecular analysis of proteins both inside and outside the cells.
Available Equipment:
CBC (Complete Blood Count) Analyzer
Flow Cytometry Device
Blood Coagulation Analyzer
Environmental Science and Biomaterials Unit
This laboratory specializes in the study of environmental materials and pollutants using various analytical techniques. Researchers aim to gain a deeper understanding of the chemical and physical properties of these materials and pollutants, as well as their potential impact on the environment and human health.
Available Equipment:
- Food Radiation Toxicity Measurement Device
- Scanning Probe Microscope (SPM)
- Radon Measurement System (RAD-7)
7. Organic and Physical Chemistry Unit:
This unit conducts research across a wide array of fields in both organic and physical chemistry. In physical chemistry, the focus includes electrochemistry, surface chemistry, catalysis, photocatalysis, materials science, engineering, and polymers. In organic chemistry, the unit specializes in the synthesis of new aromatic derivatives and the evaluation of their biological activity.
Available Equipment:
- Metallographic/Polishing Machine
- Ultrasonic Cleaner
- Multifunctional Grinder
- Combustion Furnaces
- pH Meters
- FTIR (Fourier Transform Infrared Spectrometer)
- Distillation Apparatus
8. Analytical and Inorganic Chemistry Unit
The Analytical and Inorganic Chemistry Unit conducts multifaceted research, with a focus on identifying sources of metal pollution and developing effective methods for their removal. Our work in green synthesis of new metallic nanoparticles emphasizes eco-friendly approaches, sustainability, and collaboration for industrial applications in metal-based compounds and pharmaceuticals.
Available Equipment:
- Metallographic/Polishing Machine
- Ultrasonic Cleaner
- Combustion Furnaces
- pH Meters
- Distillation Apparatus
Molecular Genetics Research Laboratory
The Molecular Genetics Research Laboratory is dedicated to studying and analyzing nucleic acids at the molecular level to enhance our understanding of genetic structures and variations in living organisms. By exploring genes and genomes, the laboratory focuses on analyzing genetic sequencing and investigates how genetic changes impact physiology and contribute to diseases.
Equipped with advanced technologies, including gene sequencing systems and DNA cloning tools, the lab enables precise extraction, replication, and analysis of genetic material.
The research team consists of molecular geneticists, scientists, and specialists who work collaboratively to analyze data and draw insightful conclusions.
As a hub for innovation in molecular genetics, the laboratory contributes significantly to expanding our knowledge of the genetic basis of biological functions and diseases, while also advancing the development of targeted therapeutic approaches.
Services Offered:
- Genetic Sequencing Analysis: Providing genetic sequencing services to determine the structure and sequence of DNA for important genes.
- DNA Cloning (PCR): Performing PCR tests to replicate and amplify specific genes for diagnostic or research purposes.
- Genetic Screening Analysis: Offering genetic screening services to assess genetic risks and detect specific genetic mutations.
- Gene Expression Analysis: Studying gene expression levels and methods to understand how they affect cellular functions and metabolism.
- Genetic Mutation Evaluation: Detecting and analyzing genetic mutations to understand their functional and health-related consequences.
- Whole Genome Analysis: Conducting comprehensive genome analysis to examine the entire genetic sequence and identify genetic variations.
- Early Diagnosis Tests: Providing diagnostic tests to assess the risk of inherited diseases at an early stage.
Available Equipment:
- Genetic Sequencing Analyzer
- Real-Time Polymerase Chain Reaction (PCR) Machine
- Polymerase Chain Reaction (PCR) Machine
- Gel Electrophoresis Apparatus
- Sanger Sequencing Machine
- Automated DNA Extraction System
- Microarray Cellular Scanning System
Biobank (Nourah Biobank for Biological Tissues)
Nourah Biobank seeks to serve as a reliable reference for diverse biological samples, especially tissues linked to health data, for researchers and students around the world. In collaboration with numerous institutions and healthcare centers, the biobank collects a wide range of samples and health data, providing researchers with the support and motivation necessary to engage with biobanks and contribute to advancements in medicine and health research.
Services Offered:
1- Advanced Imaging
The Advanced Imaging Unit at Nourah Biobank for Biological Tissues provides researchers in health sciences with access to a comprehensive set of cutting-edge tools, ensuring high-quality services. The unit is equipped with the following instruments:
• Scanning Electron Microscope (SEM)
• Transmission Electron Microscope (TEM)
• Confocal Microscope
• Micro CT SkyScan Device
2- Pathological Anatomy
The Histology and Cytopathology Unit provides various techniques for tissue and cell processing, embedding, sectioning, and staining, using a range of the best equipment that serves different types of tissue and cell samples, including:
- Dissection Table
- Microtome
- Automated Slide Staining Machine
- Tissue Processor
- Tissue Embedding
Cryostat (Frozen Section Microtome)
3- Storage Services
Nourah Biobank offers secure storage facilities that are monitored 24/7, with an integrated backup power system. Regular checks of the system and environmental conditions are performed to maintain sample quality. This enables the biobank to store both researcher samples and the biobank's own collections through our specialized platform, which includes:
- 20°C Freezer
- -80°C Freezer
- Liquid Nitrogen Freezer rewrite
4- Health Records and Data
Nourah Biobank offers access to authorized health data of volunteers, with all samples linked to their respective health records. Such records are regularly updated, and volunteer identities are fully anonymized to ensure privacy and confidentiality.
5- Education and Training
Nourah Biobank offers a dynamic environment for educational and professional growth, supported by its modern infrastructure and highly skilled team. Thus, it provides a unique experience for students, trainees, and researchers, helping them improve their laboratory skills and foster their research innovations.
Lifestyle and Health Research Department:
The Lifestyle and Health Research Laboratories at Princess Nourah bint Abdulrahman University were founded in 2019 as the first research center in the region dedicated exclusively to studying lifestyle behaviors and health, with a particular focus on the health of children, adolescents, and women. Located within the Health Sciences Research Center, next to King Abdullah University Hospital, the facility includes two large laboratories, along with additional spaces for administrative offices, meeting rooms, statistical analysis, research, and interview and evaluation offices.
In the fourth quarter of 2022, the following departments were established within the Lifestyle and Health Research department:
1- The Sports Medicine Department
2- The Community Health Department
Sports Medicine Department
As a core component within the Lifestyle and Health Research Department, the Sports Medicine Department aims to address gaps in local and regional research on sports assessment, treatment, and prevention. It is focused on providing optimal care for individuals involved in sports and fitness activities, with a particular emphasis on women's sports. Hence, the department plays a vital role in enhancing the athletic performance of female athletes across various disciplines.
Services Offered:
· Performing physiological assessments and providing tailored consultations.
· Providing high-level training in research methodologies and the practical application of laboratory measurements.
· Encouraging and supporting collaborative research in sports medicine, both in laboratory settings and through field studies.
Available Equipment:
Cardiopulmonary and Metabolic Function Measurement Devices:
• An integrated system for measuring cardiopulmonary and metabolic functions, capable of assessing resting metabolic rate.
• Two complete devices for measuring gas volumes and remote respiration with GPS integration.
• Treadmill for measuring physical exertion, equipped with a safety harness.
• Several devices for assessing exertion using various types of exercise bikes, including those designed for pediatric exertion testing.
• Resting electrocardiogram (ECG) device with 12-lead (electrode) configuration.
• Three-lead ECG device integrated with the cardiopulmonary function measurement system.
• Vital sign measurement devices, including heart rate, blood pressure, and body temperature monitoring.
Musculoskeletal Function Measurement Devices:
• Devices for measuring muscular strength at constant velocity, assessing both static and dynamic (positive and negative) muscle forces (towards and away from the muscle's center).
• Electronic devices for measuring grip strength in both children and adults.
• Device for measuring muscle strength during vertical jumping.
• Exercise bike for assessing muscular power and muscular endurance.
• Multi-station muscle training and strengthening device, targeting the chest, shoulders, back, thighs, and arms.
Body Composition Measurement Devices:
· Dual-energy X-ray absorptiometry (DEXA) device for measuring bone density and visceral fat percentage.
· Body composition analyzer (measuring fat percentage, muscle mass, and intra- and extracellular water content) using bioelectrical impedance analysis (BIA).
· Harpenden and Lange skinfold calipers for measuring skinfold thickness.
· Research-grade body weight and height measurement devices.
· Device for measuring abdominal circumference.
Body Balance and Responsiveness Measurement Devices:
- Body balance measurement platform during dynamic movement
- Total body response speed (reaction time) measurement device with audio and visual alarms
Flexibility and Body Measurement Devices:
- Device for measuring flexibility in various minor and major joints
- Set of boxes for measuring flexibility while sitting and extending arms forward
- Complete body measurement kit for measuring lengths, widths, and circumferences of upper and lower body parts
Devices for Measuring Glucose and Lactic Acid in Blood during Rest and Physical Activity:
Community Health Department
The Community Health Department focuses on addressing research needs in areas related to lifestyle and health, such as physical activity, sedentary behavior, sleep, nutrition, and mental well-being. It also seeks to promote research on lifestyle, health, and non-communicable diseases, aiming to identify non-pharmacological methods of prevention and treatment that benefit both individuals and the broader community.
Equipped with a variety of tools and equipment, the department's laboratories support a wide range of vital tests, as outlined below. Additionally, the department's staff is trained to provide comprehensive research consultation across all stages of community health studies, from survey-based research to clinical trials.
Services Offered:
- Conducting physiological measurements and providing relevant consultations.
- Offering advanced training in scientific research skills, with a focus on the practical application of laboratory measurements.
- Encouraging collaborative research in community health, both within laboratory environments and through field-based studies.
- Raising public awareness within both internal and external communities, while promoting healthy lifestyle behaviors.
- Contributing to the dissemination of lifestyle and health research by integrating it into both formal and informal training programs in schools and universities.
- Providing scientific evidence to support public health programs and develop strategies to improve lifestyle behaviors, addressing issues like obesity.
Available Equipment:
The laboratories are equipped with a variety of devices for conducting various measurements, including:
Cardiovascular, metabolic, and heart function measurement devices:
- Fully automatic desktop evaluation system for cardiovascular and metabolic dysfunction with a canopy for assessing energy expenditure at rest and metabolic rate.
- Two complete systems for remote gas analysis using breath-by-breath technology, with a GPS receiver.
- Research treadmill with a safety harness.
- Several bicycle ergometers, including a recumbent bike and a specialized bike for pediatric testing.
- 12-lead resting electrocardiogram (ECG).
- 3-lead exercise electrocardiogram (ECG).
- Devices for heart rate variability testing.
- Automated vital signs system for resting blood pressure, temperature, and pulse rate.
- Automated external defibrillator (AED).
- Semi-private area for venipuncture testing.
Muscle Function Measurement Devices:
- Isokinetic device: Used to measure the strength of all central and peripheral joints and to conduct isometric assessments.
- Digital handgrip dynamometer: Used to test handgrip strength in both children and adults.
- Jumping assessment system: With digital reading, used to test vertical jump capacity (muscle strength).
Body Composition Measurement Devices:
- Dual-energy X-ray absorptiometry (DXA): Used to assess bone density, visceral fat, and body fat distribution.
- Bioelectrical impedance analysis (BIA) system: Provides non-invasive evaluation of lean muscle mass, fat mass, and body water content.
- Skinfold calipers
- Height measurement devices and research scales
Balance and Reaction Time Measurement Devices
- Stability platform: Used to measure balance during dynamic movement.
- Full-body digital reaction time measurement device: Equipped with visual and auditory stimuli.
Flexibility Assessment, Anthropometric Measurements, and Blood Analysis Devices
- Multijoint range of motion measurement kit, including large and small angle goniometers.
- Portable flexibility boxes: Used to test sit-and-reach flexibility.
- Fully equipped private room: Contains a complete anthropometric measurement set to assess body length, width, and circumference, including a caliper for measuring sagittal abdominal diameter.
- Portable lactate analyzers: Used in research to measure lactate from capillary samples.
- Portable glucose analyzers: Used in research to measure blood glucose from capillary samples.
Physical Activity and Sedentary Behavior Measurement Devices
- Portable accelerometers: Used in research to assess physical activity levels.
- Miniature portable accelerometers: Specifically used in research to evaluate sitting and sleeping behaviors.
