GREEN FABRICATION OF SILVER AND MANGANESE OXIDE NANOPARTICLES USING Leucophyllum frutescens LEAF EXTRACT: CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY
Authors: Sarah Abdullah AL Masoud, Sarah Ibrahim Alnasser, Amjad Saad Alotaibi, Hessa O. Aldraiwiesh, Dhuha Alsuwaid, Kholoud A. Baeshen, Reham M. Aldahasi, Afrah E. Mohammed
Received September 6, 2024
Accepted for publication November 15, 2024
Published December 30, 2024. Volume 2:2 Pages 72—83
Checked for plagiarism Yes
Peer reviewer comments 2
Correspondence: AFAMohammed@pnu.edu.sa
Abstract
Nanotechnology is increasingly adopting green synthesis techniques, prioritizing non-toxic reaction components and mild reaction conditions to promote sustainable and environmentally friendly solutions. As a reliable alternative to conventional chemical methods, natural sources have been explored as cost-effective and eco-friendly reducing and capping agents for nanomaterial fabrication. This study explores the green synthesis of silver (AgNPs) and manganese oxide (MnONPs) nanoparticles using Leucophyllum frutescens leaf extract as an eco-friendly approach. Their antibacterial effect has been evaluated. UV-Vis spectroscopy confirmed nanoparticle formation, with AgNPs exhibiting an absorption peak at 439.32 nm and MnONPs at 304.25 nm. FTIR analysis identified functional groups at 1637 cm⁻¹ and 3344 cm⁻¹, suggesting their role in nanoparticle stabilization. Zeta potential analysis indicated that AgNPs (128 nm) and MnONPs (151.2 nm) carried a negative charge. Antimicrobial testing against Staphylococcus aureus, Klebsiella pneumoniae, and Escherichia coli demonstrated that AgNPs (1mg/mL) exhibited superior significant antibacterial activity against K. pneumoniae. These findings highlight the potential of L. frutescens-derived nanoparticles as effective antimicrobial agents, suggesting further investigation at higher concentrations for biomedical and environmental applications.
KEYWORDS: Silver; Manganese; nanoparticles; antibacterial; Escherichia coli; klebsiella pneumoniae.
